Molecular Mechanisms Underlying Detection Sensitivity in Nanoparticle-Assisted NMR Chemosensing
J. Phys. Chem. Lett. 14 (30): 6912–6918
Resume
I am currently a Senior Software Engineer at Nykode Therapeutics, where I develop scalable computational software and bioinformatics pipelines for vaccine design and neoantigen discovery. Before that, I built end-to-end AI-powered products for DN Media Group, and I built machine learning models to predict clinical outcomes from immunological data for Oslo University Hospital. I also worked for two years as a software developer at a federated learning company, Resonyx. There, I honed my programming skills by building edge and cloud infrastructures and developing analysis models that processed live audio signals. Prior to 2021, I was a full-time researcher, using numerical simulations and machine learning models to study biological systems relevant to drug development.
My passion is gathering actionable insights from real-world data and visualizing them in meaningful, stakeholder-friendly ways. My recent senior positions have also nurtured an interest in team and project management, where my directness and calmness are valuable assets.
Overall, my areas of interest are AI/ML, data science, bioinformatics and teaching. My top technologies of choice are Python, SQL, GCP/Terraform, Docker, and Apache Airflow. Spanish is my native language, and I am proficient in English and Italian. I also have good communication skills (B2) in Norwegian.
Work
Apr 2026 – PresentSenior Software EngineerNykode TherapeuticsOslo, Norway
- Led development and deployment of scalable computational software and bioinformatics pipelines (Python, SQL) for vaccine design and neoantigen discovery on AWS.
- Translated research prototypes into production-grade Python algorithms within internal platforms.
- Optimized AWS-based research infrastructure, including HPC environments and secure handling of sensitive patient data.
- Delivered and documented GxP-compliant, validated software.
Nykode Therapeutics ASA is a clinical-stage biotech company developing next-generation vaccines for cancer and autoimmune diseases.
Visit websiteJan 2025 – Mar 2026Senior AI EngineerDN Media GroupOslo, Norway
- Designed, implemented and maintained a data platform in GCP for batch and event-based data sources.
- Built end-to-end products powered by large language models and multiagent graphs.
- Built data products using SQL and DBT for the organization’s stakeholders.
- Developed end-to-end RAG-based applications for data exploration using natural language.
- Deployed and maintained web applications on GCP, optimized CI/CD workflows, and led architecture decisions for scalable, secure, and automated AI solutions across the organization.
DN Media Group is a leading Norwegian media company, leveraging AI and data-driven solutions to enhance journalism, content delivery, and business intelligence.
May 2023 – Dec 2024Senior data scientist (consultant)Oslo University Hospital – CellFiTOslo, Norway
- Designed and implemented a Python web application to process immunological data to optimize personalized cancer treatments.
- Developed an automatic pipeline to process and analyze proteomics (cytometry) data.
- Implemented front-end (Streamlit, Dash and React), database (PostgreSQL and SQLite), API (FastAPI) and parallelization (thread and multiprocess) solutions to optimize the pipeline’s performance.
- Applied supervised machine learning methods (scikit-learn) for feature extraction, biomarker identification and prediction of clinical outcomes.
- Formulated statistical models and unsupervised clustering algorithms to classify cells into subpopulations from immunological data.
- Led a team of 5 with agile methods (SCRUM).
The CellFit Project is a collaboration led by Oslo University Hospital, Department of Cellular Therapy. It seeks to address one of the biggest challenges for cell-based cancer therapy – efficient and scalable production.
Visit websiteNov 2022 – Dec 2024Biomedical outreach representative (consultant)Expert AnalyticsOslo, Norway
- Secured 5 MNOK funding from Innovation Norway for the development of Cytofit – Bridging Data collection and Clinical Applications.
- Represented Expert Analytics as member of Oslo Cancer Cluster.
- Cultivated relationships with academic and industrial organizations in the biomedical sector at notable European gatherings like Cancer Crosslink 2023 and the Nordic Precision Medicine Forum 2023.
Oslo Cancer Cluster is an oncology research and industry cluster dedicated to improving the lives of cancer patients by accelerating the development of new cancer diagnostics and treatments.
Visit websiteMar 2021 – Nov 2022Senior data scientist and backend developer (consultant)ResonyxOslo, Norway
- Analyzed terabytes of high-frequency audio to detect short-lived anomalies and slow baseline variations over time.
- Developed and deployed ML/AI models to predict failures in heavy hydropower machinery.
- Maintained an AWS cloud infrastructure, including databases (DynamoDB), long-term storage (S3), roles (IAM) and monitoring systems (CloudWatch, CodePipeline, IoT Core).
- Wrote API endpoints for CRUD operations between a frontend and cloud infrastructure.
- Contributed to developing an edge-computing product that records and analyzes, uninterruptedly, high-frequency audio (up to 48 kHz) in locations with limited internet connectivity.
- Led a team of 7 with agile methods (SCRUM) and handled direct communication with two energy companies in Norway (Statkraft AS and Agder Energi).
Edge Audio Analytics is a product developed in-house by Expert Analytics. It aims at extending the lifetime of assets through high-frequency data streams and AI-powered analysis of real-time signals.
Visit websiteMar 2021 – Dec 2024ConsultantExpert Analytics ASOslo, Norway
- See the entries above for more details on my consultancy projects.
Expert Analytics AS is a private research and development company specialising in data science and industrial digitalisation.
Visit websiteJan 2018 – Feb 2021Research collaborator – PhD fellowItalian Institute of TechnologyGenoa, Italy
- Studied the interaction between drugs and biomolecules with ML/AI and statistical inference models, in Python.
- Employed numerical simulations to study functionalized metal nanoparticles interacting with biomacromolecules.
- Targeted human and bacterial DNA topoisomerases for the development of novel anticancer and antimicrobial compounds.
- Applied statistical methods to analyze hundreds of gigabytes of data.
- Published six articles (plus three submitted and two in preparation) in peer-reviewed journals.
- Supervised 2 master’s students.
- Developed skills at project management, proposing research questions, designing experiments, programming and data analysis.
The Italian Institute of Technology is a foundation that promotes excellence in basic and applied research thus fostering Italy’s economic development. The institute is a leading organization in biotechnology, nanosciences, neurology and robotics.
Visit websiteSep 2018 – Dec 2018 and Sep 2019 – Dec 2019Guest researcherHylleraas Centre for Quantum Molecular Sciences – University of OsloOslo, Norway
- Parallelized data analysis routines in high-performance computing (HPC) environments with PBS and Slurm.
- Honed Python skills for data analysis and visualization.
- Used numerical simulations and statistical methods to study polymer aggregation.
- Wrote a systematic review on the topic of my research project.
The Hylleraas Centre is a Norwegian center of Excellence established by the Research Council of Norway. It aims to develop and apply computational methods to understand and predict new chemistry, physics and biology of molecules in complex and extreme environments.
Visit websiteJan 2017 – Jun 2017Part-time professorUniversity of the AndesBogotá, Colombia
- Professor of “Physical Chemistry Laboratory” and “General Chemistry Laboratory.”
- Graded over 50 assignments per week including lab reports, workshops, quizzes and exams.
- Encouraged student engagement by employing teaching techniques such as open discussions and interactive presentations.
- Maintained regular office hours to help students with questions and provide educational support.
The University of Los Andes is an autonomous, independent and innovative institution that fosters pluralism, tolerance and respect for ideas. It aims for academic excellence while providing rigorous critical and ethical character development.
Visit websiteJul 2013 – Dec 2016Teaching assistantUniversity of the AndesBogotá, Colombia
- Imparted 3-hour weekly lectures to 20+ students as a complement to the main sessions of various courses.
- Graded exams and workshops as requested by the supervising professor on an “on-demand” basis.
- Courses imparted: Spectroscopy and Quantum Chemistry; Computational Chemistry; Physical Chemistry II; Physical Chemistry I; Physical Chemistry Fundamentals; Analytical Chemistry Fundamentals; Introduction to the Modern Understanding of Atoms and Molecules; General Chemistry; General Physics.
Jan 2016 – Apr 2016Research internshipItalian Institute of TechnologyGenoa, Italy
- Participated in a drug discovery campaign for novel antimicrobial agents.
- Used numerical simulations to study interactions between drugs and proteins.
- Reported weekly to the principal investigator with multimedia presentations updating him on new results.
- Developed skills in Python for the processing and analysis of data.
The Italian Institute of Technology is a foundation that promotes excellence in basic and applied research thus fostering Italy’s economic development. The institute is a leading organization in biotechnology, nanosciences, neurology and robotics.
Visit website
Education
Nov 2017 – Mar 2021PhD in biotechnological, biocomputational, pharmaceutical, and pharmacological sciencesItalian Institute of TechnologyGenoa, Italy
- Graduated with honors (cum laude).
- Earned a research scholarship for carrying out the PhD studies at the Istituto Italiano di Tecnologia (IIT).
- Thesis title: Multiscale Simulations to Investigate Nanoparticle Internalization and Transport Across the Cellular Membrane.
Aug 2019 – Aug 2020Certified online courses on data science and machine learningDataCamp
- Machine Learning Scientist career track certified online course (93 h).
- Data Scientist career track certified online course (100 h).
- Python Programmer career track certified online course (52 h).
- Developed skills in data preprocessing, data visualization, linear/logistic models, SVM, CART, XGBoost, NLP and deep learning.
May 2020 – Jun 2020Certified online courses on leadership and innovationMIT Professional Education
- Five-week online course (40 h).
- Three self-paced modules covering the five technologies that govern digital transformation in organizations, i.e., artificial intelligence (AI), blockchain, the internet of things (IoT), cloud computing and cybersecurity.
- Coordinated collaborative activities with other participants around the world: three discussion forums, three reflection essays and two exams.
- The course included two seminars carried by leadership experts from MIT.
- Performed extracurricular research on how the topics of the course related to institutional organization.
Jan 2012 – Jul 2017BSc. PhysicsUniversity of the AndesBogotá, Colombia
- Member of the Computational Astrophysics research group.
- Thesis title: Simulations of a Weakly Self-Interacting Fluid by Means of Lattice Boltzmann Methods.
Aug 2011 – Dec 2016BSc. ChemistryUniversity of the AndesBogotá, Colombia
- Member of the Computational Bio-Organic Chemistry research group.
- Thesis title: Application of Molecular Mechanics for the Discovery of Novel Microbial IIA Topoisomerases Inhibitors.
Jun 2016 – Jul 2016Modern Physics at All Scales Summer SchoolLeiden UniversityLeiden, The Netherlands
- Program for undergraduate students to explore various research disciplines and applied physics under the guidance of leading experts.
- Included talks, hands-on lab tours and cultural exchange events.
- Supervised by: Prof. Dirk Bouwmeester.
Volunteering
Dec 2020 – Jun 2021TeacherFoundation for Educational Equity
- Designed a year-long introductory Python course targeting high school students in remote areas of Colombia with limited internet access.
- Provided slides and recorded teaching sessions.
Aug 2020 – May 2021TeacherUniandinos Alumni Association. Quiero Mentoría (“I Want Mentorship Program”)
- Mentor of two undergraduate students.
- Meet for 2 hours every month with each of the mentees to help them transition into a working environment or a postgraduate study program.
- Offer guidance to the mentees throughout introspective exercises to determine their motivations and interests.
Dec 2019 – PresentReviewerAmerican Chemical Society. Journal of Chemical Theory and Computation
- Peer reviewer of ca. 1 manuscript per month and comment on their potential for publication in the Journal of Chemical Theory and Computation and occasionally the Journal of Physical Chemistry.
- Receive articles for review regarding computational chemistry methodologies, nanoparticles and biotechnological sciences.
Oct 2013 – Sep 2015Students representative of the chemistry departmentUniversity of the AndesBogotá, Colombia
- Member of the board of directors as the representative to the University’s Committee of Student Affairs.
- Weekly assessment of escalated academic and disciplinary student cases.
- Assisted any student with logistic and academic questions about the university’s regulations.
- Engaged in collaborative activities to improve the communication channels between university directives and students.
Aug 2012 – Jul 2013Teacher and fundraiser for poverty alleviationSOSAndes – Students Offering SupportBogotá, Colombia
- Imparted lectures on differential calculus, physics and chemistry.
- Money raised from the lectures imparted would go to the building of houses for homeless people in rural areas of Colombia.
- Recruited students in need of academic support.
Publications
The supporting information files associated with each publication can be downloaded from the publisher’s website directly, but feel free to contact me if you have any issue ;)
NanoModeler CG: A Tool for Modeling and Engineering Functional Nanoparticles at a Coarse-Grained Resolution
J. Chem. Theory Comput. 19 (5): 1582–1591
On the Metal-Aided Catalytic Mechanism for Phosphodiester Bond Cleavage Performed by Nanozymes
ACS Catal. 11 (14): 8736–8748
Association Mechanism of Peptide-Coated Metal Nanoparticles with Model Membranes: A Coarse-Grained Study
J. Chem. Theory Comput. 17 (7): 4512–4523
NanoModeler: A Webserver for Molecular Simulations and Engineering of Nanoparticles
J. Chem. Theory Comput. 15 (3): 2022–2032
Achievements
Received a 5 MNOK grant from Innovation Norway for Cytofit – Bridging Data Collection and Clinical Applications.
Invited speaker at the Intelligent Health Conference. 2024. Oslo, Norway.
Full scholarship from Becas Santander to enroll in an online course from the Massachusetts Institute of Technology (MIT). The scholarship covered the enrollment fee of $3,200 of the MIT – Leading Digital Transformation certified course.
Receiver of the research grant HP10CR7KHL from the Italian SuperComputing Resource Allocation-Class C (ISCRA-C). Receiver of 25,000 core hours from the SuperComputing Applications and Innovation (SCAI) center.
Speaker at the Properties and Functionalities of Nanometer and Sub-Nanometer Sized Quantum Objects Gordon Research Conference. 2019. Les Diablerets, Switzerland.
Poster presentation at the New Perspectives of Nanostructured Devices and High-Resolution Characterization Techniques Gordon Research Seminar. 2019. Les Diablerets, Switzerland.
Poster presentation at the Nucleic acid immunity: from cellular mechanisms to new technologies SIBBM seminar. 2019. Bologna, Italy.
Speaker at the Challenges in modelling and simulations of nanoparticles in complex environments CECAM workshop. 2019. Genoa, Italy.
Poster presentation at the Translational and Health Informatics: Implications for Drug Discovery EuroQSAR Symposium. 2018. Thessaloniki, Greece.
Poster presentation at the Multiscale modelling in electrophysiology: from atoms to organs CECAM workshop. 2018. Lugano, Switzerland.
Poster presentation at the 1st Protein Structure, Function, and Drug Discovery School. 2017. Bogotá, Colombia.
Speaker at the 42nd Theoretical Chemists of Latin Expression Congress. 2016. Montevideo, Uruguay.
Speaker at the 6th National Congress of Theoretical and Computational Chemists. 2016. Bogotá, Colombia.
Speaker at the 2nd Colombian Congress of Biochemistry and Molecular Biology. 2016. Medellín, Colombia.